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From Warhammer 40k - Lexicanum
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After nearly a thousand years of strife and warfare, its worlds bleeding resources to fight wars elsewhere and reinforce the sector capital's defences, and infighting amongst sector nobility, the Orpheus Sector erupted in [[Orpheus Revolt|civil war]]. Rebels in the Drucillan Cluster overthrew the government and declared their secession from the sector, rallying other rebels to their cause and undermining the sector's stability. The parliament of Amraphel hired xenos mercenaries to fight their enemies, only to become the victims of the [[Khrave]] they had hired. Imperial authorities learned that the [[Chaos|Great Enemy]] had orchestrated most of the unrest{{Fn|1a}}.
In 903.M39, hope came to the fractured sector in the form of a crusade fleet. At the head of the fleet stood [[Arch-Confessor]] [[Marduk (Imperial)|Marduk]] of Helvamon. Marduk declared a [[War of Faith]] for the souls of the Orpheus Sector, claiming to have received a warning from the God-Emperor himself of a great and terrible threat to mankind rising from the darkness of the sector. The Arch-Confessor provided a figurehead and a rallying point for the resistance against the dark powers. By 921, the Imperial forces had effectively destroyed the enemy, with only one holdout on Colkasth. The [[Angels Revenant]] strike cruiser ''Intercessor'' investigated the sudden cessation of Astropathic communication with the ground forces: two extremely powerful xenos void craft ambushed it on the edge of the system, but ''Intercessor'' destroyed one and drove off the other. The damaged ship can only watch a raging battle in-system via long-range auguries and by the time ''Intercessor'' reaches orbit, the attacking force has fled, leaving Colkasth a burning, irradiated wasteland. The Angels Revenant sorted out the few survivors and the planet was renamed Saint Marduk's Bane{{Fn|1a}}.
In 819.[[M41]], a contagious madness spread across the [[Industrial World]] of [[Chemarium II]]. The [[Chaos Lord]] and self-styled "Beggar King" [[Ranker Nonesuch]] led his insane followers to destroy Imperial manufactoria and slaughter Imperial forces. Nonesuch then spread his uprising to the rest of the system. [[Inquisitorial Stormtrooper]]s were dispatched to aid the suppression campaign while an exclusion zone was established around the system.{{Fn|1a}}