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[[Image:Protiphage_Iota.jpg|thumb|right|220px|Protiphage Iota]]'''Iota''' was a '''Protiphage''' of [[Culexus AssassinTemple|Clade Culexus]] at the time of the [[Horus Heresy]]. Created in a laboratory through secretive means to copy the [[Blank|Pariah]] gene, Iota spent her entire life as a specialize [[Psyker]] killer.{{Fn|1a}} Despite this she was not a mere murderer, remembering the name of every one of her victims and remaining non-violent under normal circumstances.{{Fn|1b}} Iota was the Culexus assassin chosen to take part in the [[Execution Force]] to assassinate [[Horus]] on [[Dagonet]], where she remained indifferent and aloof to the plight of the locals and was known to vanish for days at a time in the prelude to the operation. She would show great interest in [[Venenum Temple|Venenum Assassin]] [[Jenniker Solam]] in her quest to help the local population in its civil war against traitor forces, and followed her instead of taking part in the assassination attempt against Horus.{{Fn|1c}} With Solam, Iota instead encountered the [[Daemon]] [[Blank|Pariah]] hybrid known as [[Spear]], whose presence she was able to detect. Using her [[Animus speculum]] to viciously damage Spear, Iota had the upper hand in the battle until a drop of her blood was spilt, which allowed Spear to engage his "genetic lock" and destroy her completely.{{Fn|1c}}