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===Post-Heresy===
The events of the [[Horus Heresy]] revealed weaknesses in some Legions' gene-seed. In some cases these defects had been heightened by the accelerated cultivation techniques used to keep the Legions at full strength. After the Heresy and the break-up of the original Legions, genetic banks were established on [[Terra]] to produce and store Space Marine gene-seed. These banks were to provide all genetic material for new Space Marine Chapters. To prevent cross-contamination of these genetic stocks, the gene-seed of each individual Legion was isolated, so all new Space Marines would receive gene-seed solely from one specific source. The gene-seed of the [[Traitor Legions]] was placed under a time-locked stasis seal (rather than being destroyed as many at the time assumed had happened).{{Fn|1b}}
===Subsequent Foundings===
The [[Twenty First Founding]] (also known as the '''''Cursed Founding''''') is notable in that its focus was in perfecting and removing deficiencies in flawed gene-seed. Unfortunately, many of the Chapters created at this time have developed genetic idiosyncrasies, mutations that strain the tolerance of the [[Inquisition]] and threaten these Chapters' survival.{{Fn|2}}
The [[Ultima Founding]] in [[M42]] saw tens of thousands of new [[Primaris Space Marines]] producedthanks to the efforts of [[Belisarius Cawl]]], all with the same gene-seed of the Primarchs. HoweverThanks to Cawl's [[Sangprimus Portum]], the gene-seed of the Primaris Marines is closer to that of the original Primarch's than standard versions. This and the three additional implants given to Primaris Marines have made them more genetically stable, enabling gene-seed production at rates not seen since the time of the Emperor.{{Fn|9}}
==Implantation and Reproduction==