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|Casualties3 = 8 billion Isstvanians{{Fn|1}}
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The '''Battle of Isstvan III''' was the start of the [[Horus Heresy]] and was fought between the [[Adeptus Astartes]] loyal to the [[Emperor of Mankind]] and those traitors that swore fealty to [[Imperial Guard Hierarchy#Warmaster|Warmaster]] [[Horus]].{{cite thisFn|1a}}
==History==