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Fabius joined several Emperor's Children commanders such as [[Lucius (Emperor's Children)|Lucius]] and [[Marius Vairosean]] in using extreme torture to exorcise the Daemon that was inhabiting Fulgrim.{{Fn|11}}
At his Primarch's demand, Fabius produced his first cloned Primarch, creating a replica of [[Ferrus Manus]] which Fulgrim tried to again convert to his cause and killing him after he refused. Fabius created multiple clones of Ferrus, all refusing Fulgrim before being killed.{{Fn|13}} Fabius proved vital for the Emperor's Children during the Heresy, reviving both [[Eidolon]] and Lucius at the demand of their Primarch. As the war ground on his experiments became more and more depraved, torturing captive Space Marines of both allied and enemy Legions to give birth to his first generation of [[Terata]].{{Fn|1414b}}
During the end of the Heresy Fabius took part in his legion's attack on [[Terra]], although neither he or his Legion were actually involved in the siege of the [[Imperial Palace]]; instead, they attacked the general population. In the Legion's unrestrained fervour, millions of Earth's civilians were murdered. Bile used the opportunity to perform horrific experiments on captives. [[Human]] victims were rendered down to create special drugs which heightened the Legionnaires' feeling of ecstasy. It is possible that Earth served as the first example of Fabius' subsequent atrocious experiments on entire planetary populations.{{Fn|5}} During the [[Siege of Terra]], Fabius had an epiphany, seeing the uselessness of what the traitor Legions were trying to accomplish he left Terra before the death of [[Horus]], along with a retinue of altered followers. The act incensed Fulgrim, who put a bounty on his head.{{Fn|18e}} Bile was meanwhile hunted by the [[Salamanders]], and [[Hunt For Bile|narrowly escaped their wrath]].{{Fn|24}}
**[[Fulgrim]]
**[[Horus]]{{Fn|16}}
*[[Eidolon (Emperor's Children)|Eidolon]] — As well as his early work using [[Laer]] technology to give the [[Lord Commander]] the ability to emit a nerve paralysing shriek,{{Fn|10a}} following Eidolon's execution Fabius managed to reattach his severed head to his body and revive him.{{Fn|1414a}}
*[[Enhanced Warrior|Terata]] — His experiments on others bring uncertain results. Sometimes the experiment is a success, creating psychotic killers, superhuman even in comparison to their corrupted [[Chaos]] brethren, sometimes the subject's metabolism disintegrates in the face of the stress, resulting in instant death.{{CME}} He has become fascinated with the new [[Primaris Space Marines]], and has obsessively dissected and studies whatever specimens he has captured. He has pledged to create his own twisted versions of the Primaris.{{Fn|15}}
*[[Kakophoni]] — The original Noise Marines.{{Fn|18f}}
*{{Endn|12}}: [[Fulgrim: The Palatine Phoenix (Novel)]], Chapter Two
*{{Endn|13}}: [[Imperfect (Short Story)]]
*{{Endn|14}}: [[Angel Exterminatus (Novel)]]:**{{CMEendn|14a}}: ch. 8**{{endn|14b}}: ch. 14
*{{Endn|15}}: [[Codex: Chaos Space Marines (8th Edition)]], pg. 86 — ''Fabius Bile''
*{{Endn|16}}: [[The Talon of Horus (Novel)]], Chapter 19